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Comprehensive Interrogation of Natural TALE DNA Binding Modules and Transcriptional Repressor Domains
Transcription activator-like effectors (TALE) are sequence-specific DNA binding proteins that harbor modular, repetitive DNA binding domains. TALEs have enabled the creation of customizable designer transcriptional factors and sequence-specific nucleases for genome engineering. Here we report two im...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556390/ https://ncbi.nlm.nih.gov/pubmed/22828628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1962 |
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