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Graded or threshold response of the tet-controlled gene expression: all depends on the concentration of the transactivator

BACKGROUND: Currently, the step-wise integration of tet-dependent transactivator and tet-responsive expression unit is considered to be the most promising tool to achieve stable tet-controlled gene expression in cell populations. However, disadvantages of this strategy for integration into primary c...

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Detaylı Bibliyografya
Asıl Yazarlar: Heinz, Niels, Hennig, Katharina, Loew, Rainer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556329/
https://ncbi.nlm.nih.gov/pubmed/23336718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-5
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