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Improved single-chain transactivators of the Tet-On gene expression system
BACKGROUND: The Tet-Off (tTA) and Tet-On (rtTA) regulatory systems are widely applied to control gene expression in eukaryotes. Both systems are based on the Tet repressor (TetR) from transposon Tn10, a dimeric DNA-binding protein that binds to specific operator sequences (tetO). To allow the indepe...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797012/ https://ncbi.nlm.nih.gov/pubmed/17239234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-6 |
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