Improved single-chain transactivators of the Tet-On gene expression system

BACKGROUND: The Tet-Off (tTA) and Tet-On (rtTA) regulatory systems are widely applied to control gene expression in eukaryotes. Both systems are based on the Tet repressor (TetR) from transposon Tn10, a dimeric DNA-binding protein that binds to specific operator sequences (tetO). To allow the indepe...

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Detalhes bibliográficos
Main Authors: Zhou, Xue, Symons, Jori, Hoppes, Rieuwert, Krueger, Christel, Berens, Christian, Hillen, Wolfgang, Berkhout, Ben, Das, Atze T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797012/
https://ncbi.nlm.nih.gov/pubmed/17239234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-6
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