Graded transcriptional response to different concentrations of a single transactivator

Threshold mechanisms of transcriptional activation are thought to be critical for translating continuous gradients of extracellular signals into discrete all-or-none cellular responses, such as mitogenesis and differentiation. Indeed, unequivocal evidence for a graded transcriptional response in whi...

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Autors principals: Kringstein, Andrew M., Rossi, Fabio M. V., Hofmann, Andreas, Blau, Helen M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24877/
https://ncbi.nlm.nih.gov/pubmed/9811858
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