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Suppression of rds Expression by siRNA and Gene Replacement Strategies for Gene Therapy Using rAAV Vector
Small interfering RNA (siRNA) is a promising tool for the treatment of dominant diseases. Autosomal dominant eye disease like retinitis pigmentosa, are a leading cause of blindness. Mutations in rds/peripherin lead to the degeneration of photoreceptors and are associated with several autosomal retin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556273/ https://ncbi.nlm.nih.gov/pubmed/22183336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-0631-0_29 |
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