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Suppression of Mouse Rhodopsin Expression in Vivo by AAV Mediated siRNA Delivery
PURPOSE: The purpose of this study is to demonstrate that the expression of rhodopsin can be down regulated in vivo by AAV-delivered siRNA. This is the first step in an RNA replacement strategy for the allele-independent treatment of Autosomal Dominant Retinitis Pigmentosa (ADRP). METHODS: HEK 293 c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892214/ https://ncbi.nlm.nih.gov/pubmed/17292939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2006.11.026 |
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