Generation of Biologically Active Multi-Sialylated Recombinant Human EPOFc in Plants

Hyperglycosylated proteins are more stable, show increased serum half-life and less sensitivity to proteolysis compared to non-sialylated forms. This applies particularly to recombinant human erythropoietin (rhEPO). Recent progress in N-glycoengineering of non-mammalian expression hosts resulted in...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Castilho, Alexandra, Neumann, Laura, Gattinger, Pia, Strasser, Richard, Vorauer-Uhl, Karola, Sterovsky, Thomas, Altmann, Friedrich, Steinkellner, Herta
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555983/
https://ncbi.nlm.nih.gov/pubmed/23372778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054836
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы