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Enzymatic Analysis of Tet Proteins: Key Enzymes in the Metabolism of DNA Methylation
One of the most exciting recent advances in the epigenetic field is the discovery that 5-methylcytosine (5mC) in DNA can be iteratively oxidized by a family of proteins known as Tet proteins to generate 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). These 5mC...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555433/ https://ncbi.nlm.nih.gov/pubmed/22910204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-391940-3.00005-6 |
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