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Typical Cell Signaling Response to Ionizing Radiation: DNA Damage and Extranuclear Damage
To treat many types of cancer, ionizing radiation (IR) is primarily used as external-beam radiotherapy, brachytherapy, and targeted radionuclide therapy. Exposure of tumor cells to IR can induce DNA damage as well as generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) whi...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag Berlin Heidelberg
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555267/ https://ncbi.nlm.nih.gov/pubmed/23357898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11670-012-0083-1 |
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