The RAS Guanyl Nucleotide-releasing Protein RasGRP1 Is Involved in Lymphatic Development in Zebrafish

The molecular basis of the lymphatic development remains largely unknown. Using zebrafish as a model, we discovered a novel role for the Ras guanine-releasing protein 1 (RasGRP1), a protein involved in Ras activation in lymphangiogenesis. Secondary lymphatic sprouts from the posterior cardinal vein...

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Bibliografiske detaljer
Main Authors: Huang, Heng, Jin, Ting, Wang, Lin, Wang, Fulong, Zhang, Rui, Pan, Yi, Wang, Zhenzhen, Chen, Yan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554906/
https://ncbi.nlm.nih.gov/pubmed/23184941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418202
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