Yeast Eukaryotic Initiation Factor 4B (eIF4B) Enhances Complex Assembly between eIF4A and eIF4G in Vivo

Translation initiation factor eIF4F (eukaryotic initiation factor 4F), composed of eIF4E, eIF4G, and eIF4A, binds to the m(7)G cap structure of mRNA and stimulates recruitment of the 43S preinitiation complex and subsequent scanning to the initiation codon. The HEAT domain of eIF4G stabilizes the ac...

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Autores principales: Park, Eun-Hee, Walker, Sarah E., Zhou, Fujun, Lee, Joseph M., Rajagopal, Vaishnavi, Lorsch, Jon R., Hinnebusch, Alan G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554905/
https://ncbi.nlm.nih.gov/pubmed/23184954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398537
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