Essential Role of Class II Phosphatidylinositol-3-kinase-C2α in Sphingosine 1-Phosphate Receptor-1-mediated Signaling and Migration in Endothelial Cells

The phosphatidylinositol (PtdIns) 3-kinase (PI3K) family regulates diverse cellular processes, including cell proliferation, migration, and vesicular trafficking, through catalyzing 3′-phosphorylation of phosphoinositides. In contrast to class I PI3Ks, including p110α and p110β, functional roles of...

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Main Authors: Biswas, Kuntal, Yoshioka, Kazuaki, Asanuma, Ken, Okamoto, Yasuo, Takuwa, Noriko, Sasaki, Takehiko, Takuwa, Yoh
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554904/
https://ncbi.nlm.nih.gov/pubmed/23192342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409656
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