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RNAi triggered by specialized machinery silences developmental genes and retrotransposons
RNAi is a conserved mechanism in which small interfering RNAs (siRNAs) guide the degradation of cognate RNAs, but also promote heterochromatin assembly at repetitive DNA elements such as centromeric repeats(1,2). However, the full extent of RNAi functions and its endogenous targets have not been exp...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554839/ https://ncbi.nlm.nih.gov/pubmed/23151475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11716 |
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