RNAi triggered by specialized machinery silences developmental genes and retrotransposons

RNAi is a conserved mechanism in which small interfering RNAs (siRNAs) guide the degradation of cognate RNAs, but also promote heterochromatin assembly at repetitive DNA elements such as centromeric repeats(1,2). However, the full extent of RNAi functions and its endogenous targets have not been exp...

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Detaylı Bibliyografya
Asıl Yazarlar: Yamanaka, Soichiro, Mehta, Sameet, Reyes-Turcu, Francisca E., Zhuang, Fanglei, Fuchs, Ryan T., Rong, Yikang, Robb, Gregory B., Grewal, Shiv I. S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554839/
https://ncbi.nlm.nih.gov/pubmed/23151475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11716
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