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Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin
Heterochromatin assembly at fission yeast centromeres involves a self-reinforcing loop mechanism wherein chromatin-bound RNAi factors facilitate targeting of Clr4–Rik1 methyltransferase. However, the initial nucleation of heterochromatin has remained elusive. We show that cells lacking Mlo3, a prote...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190054/ https://ncbi.nlm.nih.gov/pubmed/21892171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2122 |
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