FANC Pathway Promotes UV-Induced Stalled Replication Forks Recovery by Acting Both Upstream and Downstream Polη and Rev1

To cope with ultraviolet C (UVC)-stalled replication forks and restart DNA synthesis, cells either undergo DNA translesion synthesis (TLS) by specialised DNA polymerases or tolerate the lesions using homologous recombination (HR)-based mechanisms. To gain insight into how cells manage UVC-induced st...

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Bibliographic Details
Main Authors: Renaud, Emilie, Rosselli, Filippo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554758/
https://ncbi.nlm.nih.gov/pubmed/23365640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053693
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