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A Hybrid Likelihood Model for Sequence-Based Disease Association Studies
In the past few years, case-control studies of common diseases have shifted their focus from single genes to whole exomes. New sequencing technologies now routinely detect hundreds of thousands of sequence variants in a single study, many of which are rare or even novel. The limitation of classical...
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Główni autorzy: | , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science
2013
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554549/ https://ncbi.nlm.nih.gov/pubmed/23358228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003224 |
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