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A Hybrid Likelihood Model for Sequence-Based Disease Association Studies

In the past few years, case-control studies of common diseases have shifted their focus from single genes to whole exomes. New sequencing technologies now routinely detect hundreds of thousands of sequence variants in a single study, many of which are rare or even novel. The limitation of classical...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chen, Yun-Ching, Carter, Hannah, Parla, Jennifer, Kramer, Melissa, Goes, Fernando S., Pirooznia, Mehdi, Zandi, Peter P., McCombie, W. Richard, Potash, James B., Karchin, Rachel
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554549/
https://ncbi.nlm.nih.gov/pubmed/23358228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003224
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