Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of τ Protein Following Onset of Diabetes in NOD Mice

The histopathological hallmarks of Alzheimer disease (AD) include intraneuronal neurofibrillary tangles composed of abnormally hyperphosphorylated τ protein. Insulin dysfunction might influence AD pathology, as population-based and cohort studies have detected higher AD incidence rates in diabetic p...

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Detalhes bibliográficos
Main Authors: Papon, Marie-Amélie, El Khoury, Noura B., Marcouiller, François, Julien, Carl, Morin, Françoise, Bretteville, Alexis, Petry, Franck R., Gaudreau, Simon, Amrani, Abdelaziz, Mathews, Paul M., Hébert, Sébastien S., Planel, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554372/
https://ncbi.nlm.nih.gov/pubmed/22961084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0187
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