Dexmedetomidine Increases Tau Phosphorylation Under Normothermic Conditions In Vivo and In Vitro

There is developing interest in the potential association between anesthesia and the onset and progression of Alzheimer's disease. Several anesthetics have thus been demonstrated to induce tau hyperphosphorylation, an effect mostly mediated by anesthesia-induced hypothermia. Here, we tested the...

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Vydáno v:Neurobiol Aging
Hlavní autoři: Whittington, Robert A., Virág, László, Gratuze, Maud, Petry, Franck R., Noël, Anastasia, Poitras, Isabelle, Truchetti, Geoffrey, Marcouiller, François, Papon, Marie-Amélie, Khoury, Noura El, Wong, Kevin, Bretteville, Alexis, Morin, Françoise, Planel, Emmanuel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465078/
https://ncbi.nlm.nih.gov/pubmed/26058840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.05.002
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