Dexmedetomidine Increases Tau Phosphorylation Under Normothermic Conditions In Vivo and In Vitro

There is developing interest in the potential association between anesthesia and the onset and progression of Alzheimer's disease. Several anesthetics have thus been demonstrated to induce tau hyperphosphorylation, an effect mostly mediated by anesthesia-induced hypothermia. Here, we tested the...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Whittington, Robert A., Virág, László, Gratuze, Maud, Petry, Franck R., Noël, Anastasia, Poitras, Isabelle, Truchetti, Geoffrey, Marcouiller, François, Papon, Marie-Amélie, Khoury, Noura El, Wong, Kevin, Bretteville, Alexis, Morin, Françoise, Planel, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465078/
https://ncbi.nlm.nih.gov/pubmed/26058840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.05.002
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