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Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

Autophagy is a lysosomal degradation pathway important for cellular homeostasis, mammalian development, cancer and immunity. Many molecular components of autophagy have been identified, but little is known about regulatory mechanisms controlling their effector functions. Here, we show that, in contr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Keil, E, Höcker, R, Schuster, M, Essmann, F, Ueffing, N, Hoffman, B, Liebermann, D A, Pfeffer, K, Schulze-Osthoff, K, Schmitz, I
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554344/
https://ncbi.nlm.nih.gov/pubmed/23059785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.129
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