Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

Autophagy is a lysosomal degradation pathway important for cellular homeostasis, mammalian development, cancer and immunity. Many molecular components of autophagy have been identified, but little is known about regulatory mechanisms controlling their effector functions. Here, we show that, in contr...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Keil, E, Höcker, R, Schuster, M, Essmann, F, Ueffing, N, Hoffman, B, Liebermann, D A, Pfeffer, K, Schulze-Osthoff, K, Schmitz, I
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554344/
https://ncbi.nlm.nih.gov/pubmed/23059785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.129
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires