p53 Counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition

The process of somatic cell reprogramming is gaining increasing interest as reprogrammed cells are considered to hold a great therapeutic potential. However, with current technologies this process is relatively inefficient. Recent studies reported that inhibition of the p53 tumor suppressor profound...

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Autors principals: Brosh, R, Assia-Alroy, Y, Molchadsky, A, Bornstein, C, Dekel, E, Madar, S, Shetzer, Y, Rivlin, N, Goldfinger, N, Sarig, R, Rotter, V
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554331/
https://ncbi.nlm.nih.gov/pubmed/22996684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.125
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