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Single-molecule FRET analysis of DNA binding and bending by yeast HMGB protein Nhp6A

High-mobility group B (HMGB) proteins bind duplex DNA without sequence specificity, facilitating the formation of compact nucleoprotein structures by increasing the apparent flexibility of DNA through the introduction of DNA kinks. It has remained unclear whether HMGB binding and DNA kinking are sim...

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Bibliographic Details
Main Authors: Coats, Julie E., Lin, Yuyen, Rueter, Emily, Maher, L. James, Rasnik, Ivan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554232/
https://ncbi.nlm.nih.gov/pubmed/23221634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1208
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