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Single molecule FRET shows uniformity in TBP-induced DNA bending and heterogeneity in bending kinetics()
TATA binding protein (TBP) is a key component of the eukaryotic RNA polymerase II (Pol II) transcription machinery that binds to TATA boxes located in the core promoter regions of many genes. Structural and biochemical studies have shown that when TBP binds DNA, it sharply bends the DNA. We used sin...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3551999/ https://ncbi.nlm.nih.gov/pubmed/22934924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300491j |
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