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Single-molecule FRET analysis of DNA binding and bending by yeast HMGB protein Nhp6A

High-mobility group B (HMGB) proteins bind duplex DNA without sequence specificity, facilitating the formation of compact nucleoprotein structures by increasing the apparent flexibility of DNA through the introduction of DNA kinks. It has remained unclear whether HMGB binding and DNA kinking are sim...

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Hlavní autoři: Coats, Julie E., Lin, Yuyen, Rueter, Emily, Maher, L. James, Rasnik, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554232/
https://ncbi.nlm.nih.gov/pubmed/23221634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1208
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