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Steroidogenic Factor 1 (NR5A1) Maintains Centrosome Homeostasis in Steroidogenic Cells by Restricting Centrosomal DNA-Dependent Protein Kinase Activation

Steroidogenic factor 1 (SF-1 or NR5A1) is a nuclear receptor that controls adrenogenital cell growth and differentiation. Adrenogenital primordial cells from SF-1 knockout mice die of apoptosis, but the mechanism by which SF-1 regulates cell survival is not entirely clear. Besides functioning in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Chia-Yih, Kao, Yung-Hsin, Lai, Pao-Yen, Chen, Wei-Yi, Chung, Bon-chu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554211/
https://ncbi.nlm.nih.gov/pubmed/23166296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01064-12
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