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NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and β-catenin accumulation
BACKGROUND: Adrenogonadal cell growth and differentiation are controlled by nuclear receptor NR5A1 (Ad4BP/SF-1) that regulates the expression of adrenal and gonadal genes. In addition, SF-1 also resides in the centrosome and controls centrosome homeostasis by restricting the activity of centrosomal...
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| Publicado no: | Cell Commun Signal |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262199/ https://ncbi.nlm.nih.gov/pubmed/25421435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0055-9 |
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