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Amino Acid Exchanges in the Putative Nuclear Export Signal of Adenovirus Type 5 L4-100K Severely Reduce Viral Progeny due to Effects on Hexon Biogenesis

The adenovirus type 5 nonstructural L4-100K protein is indispensable for efficient lytic infection. During the late phase, L4-100K promotes selective translation of viral late transcripts and mediates the trimerization of the major capsid protein hexon. In the present study, the role of a potential...

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Bibliografiset tiedot
Päätekijät: Koyuncu, Orkide O., Speiseder, Thomas, Dobner, Thomas, Schmid, Melanie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2013
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554178/
https://ncbi.nlm.nih.gov/pubmed/23175361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02061-12
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