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Arginine Methylation of Human Adenovirus Type 5 L4 100-Kilodalton Protein Is Required for Efficient Virus Production

The adenovirus type 5 (Ad5) late region 4 (L4) 100-kDa nonstructural protein (L4-100K) mediates inhibition of cellular protein synthesis and selective translation of tripartite leader (TL)-containing viral late mRNAs via ribosome shunting. In addition, L4-100K has been implicated in the trimerizatio...

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Autors principals: Koyuncu, Orkide Ö., Dobner, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682095/
https://ncbi.nlm.nih.gov/pubmed/19264777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02493-08
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