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The IE2 60-Kilodalton and 40-Kilodalton Proteins Are Dispensable for Human Cytomegalovirus Replication but Are Required for Efficient Delayed Early and Late Gene Expression and Production of Infectious Virus

The human cytomegalovirus (HCMV) IE2 86-kDa protein is an essential transactivator of viral and cellular gene expression. Additional proteins of 60 and 40 kDa are expressed from the IE2 gene at late times postinfection and are identical to the C terminus of IE2 86. We have constructed HCMV recombina...

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Detalhes bibliográficos
Main Authors: White, Elizabeth A., Del Rosario, Christia J., Sanders, Rebecca L., Spector, Deborah H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865986/
https://ncbi.nlm.nih.gov/pubmed/17202222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02454-06
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