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The Hemagglutinin Protein of Highly Pathogenic H5N1 Influenza Viruses Overcomes an Early Block in the Replication Cycle To Promote Productive Replication in Macrophages

Macrophages are known to be one of the first lines of defense against influenza virus infection. However, they may also contribute to severe disease caused by the highly pathogenic avian (HPAI) H5N1 influenza viruses. One reason for this may be the ability of certain influenza virus strains to produ...

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Hlavní autoři: Cline, Troy D., Karlsson, Erik A., Seufzer, Bradley J., Schultz-Cherry, Stacey
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554171/
https://ncbi.nlm.nih.gov/pubmed/23152519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02682-12
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