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The Hemagglutinin Protein of Highly Pathogenic H5N1 Influenza Viruses Overcomes an Early Block in the Replication Cycle To Promote Productive Replication in Macrophages

Macrophages are known to be one of the first lines of defense against influenza virus infection. However, they may also contribute to severe disease caused by the highly pathogenic avian (HPAI) H5N1 influenza viruses. One reason for this may be the ability of certain influenza virus strains to produ...

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Detalhes bibliográficos
Main Authors: Cline, Troy D., Karlsson, Erik A., Seufzer, Bradley J., Schultz-Cherry, Stacey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554171/
https://ncbi.nlm.nih.gov/pubmed/23152519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02682-12
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