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Inhibition of Influenza A Virus Replication by Compounds Interfering with the Fusogenic Function of the Viral Hemagglutinin

Several compounds that specifically inhibited replication of the H1 and H2 subtypes of influenza virus type A were identified by screening a chemical library for antiviral activity. In single-cycle infections, the compounds inhibited virus-specific protein synthesis when added before or immediately...

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Detalhes bibliográficos
Main Authors: Plotch, Stephen J., O’Hara, Bryan, Morin, John, Palant, Olga, LaRocque, James, Bloom, Jonathan D., Lang, Stanley A., DiGrandi, Martin J., Bradley, Mary, Nilakantan, Ramaswamy, Gluzman, Yakov
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103817/
https://ncbi.nlm.nih.gov/pubmed/9847316
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