Differential Requirements for HIV-1 Vif-Mediated APOBEC3G Degradation and RUNX1-Mediated Transcription by Core Binding Factor Beta

Core binding factor beta (CBFβ), a transcription regulator through RUNX binding, was recently reported critical for Vif function. Here, we mapped the primary functional domain important for Vif function to amino acids 15 to 126 of CBFβ. We also revealed that different lengths and regions are require...

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Bibliographic Details
Main Authors: Du, Juan, Zhao, Ke, Rui, Yajuan, Li, Peng, Zhou, Xiaohong, Zhang, Wenyan, Yu, Xiao-Fang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554157/
https://ncbi.nlm.nih.gov/pubmed/23175372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02199-12
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