Core-Binding Factor Subunit Beta Is Not Required for Non-Primate Lentiviral Vif-Mediated APOBEC3 Degradation

Viral infectivity factor (Vif) is required for lentivirus fitness and pathogenicity, except in equine infectious anemia virus (EIAV). Vif enhances viral infectivity by a Cullin5-Elongin B/C E3 complex to inactivate the host restriction factor APOBEC3. Core-binding factor subunit beta (CBF-β) is a ce...

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Bibliographic Details
Main Authors: Ai, Youwei, Zhu, Dantong, Wang, Cuihui, Su, Chao, Ma, Jian, Ma, Jianzhang, Wang, Xiaojun
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178706/
https://ncbi.nlm.nih.gov/pubmed/25122780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01924-14
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