Cyclophilin Inhibitors Block Arterivirus Replication by Interfering with Viral RNA Synthesis

Virus replication strongly depends on cellular factors, in particular, on host proteins. Here we report that the replication of the arteriviruses equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) is strongly affected by low-micromolar concentrations of cycl...

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Autores principales: de Wilde, Adriaan H., Li, Yanhua, van der Meer, Yvonne, Vuagniaux, Grégoire, Lysek, Robert, Fang, Ying, Snijder, Eric J., van Hemert, Martijn J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554155/
https://ncbi.nlm.nih.gov/pubmed/23152531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02078-12
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