Cyclophilin Inhibitors Block Arterivirus Replication by Interfering with Viral RNA Synthesis

Virus replication strongly depends on cellular factors, in particular, on host proteins. Here we report that the replication of the arteriviruses equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) is strongly affected by low-micromolar concentrations of cycl...

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Autors principals: de Wilde, Adriaan H., Li, Yanhua, van der Meer, Yvonne, Vuagniaux, Grégoire, Lysek, Robert, Fang, Ying, Snijder, Eric J., van Hemert, Martijn J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554155/
https://ncbi.nlm.nih.gov/pubmed/23152531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02078-12
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