Cyclophilin Inhibitors Block Arterivirus Replication by Interfering with Viral RNA Synthesis

Virus replication strongly depends on cellular factors, in particular, on host proteins. Here we report that the replication of the arteriviruses equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) is strongly affected by low-micromolar concentrations of cycl...

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Detalhes bibliográficos
Main Authors: de Wilde, Adriaan H., Li, Yanhua, van der Meer, Yvonne, Vuagniaux, Grégoire, Lysek, Robert, Fang, Ying, Snijder, Eric J., van Hemert, Martijn J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554155/
https://ncbi.nlm.nih.gov/pubmed/23152531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02078-12
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