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Comprehensive Mutational Analysis Reveals p6(Gag) Phosphorylation To Be Dispensable for HIV-1 Morphogenesis and Replication

The structural polyprotein Gag of human immunodeficiency virus type 1 (HIV-1) is necessary and sufficient for formation of virus-like particles. Its C-terminal p6 domain harbors short peptide motifs that facilitate virus release from the plasma membrane and mediate incorporation of the viral Vpr pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Radestock, Benjamin, Morales, Ivonne, Rahman, Sheikh Abdul, Radau, Sonja, Glass, Bärbel, Zahedi, René Peiman, Müller, Barbara, Kräusslich, Hans-Georg
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554071/
https://ncbi.nlm.nih.gov/pubmed/23115284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02162-12
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