The Nucleocapsid Domain of Gag Is Dispensable for Actin Incorporation into HIV-1 and for Association of Viral Budding Sites with Cortical F-Actin

Actin and actin-binding proteins are incorporated into HIV-1 particles, and F-actin has been suggested to bind the NC domain in HIV-1 Gag. Furthermore, F-actin has been frequently observed in the vicinity of HIV-1 budding sites by cryo-electron tomography (cET). Filamentous structures emanating from...

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Autors principals: Stauffer, Sarah, Rahman, Sheikh Abdul, de Marco, Alex, Carlson, Lars-Anders, Glass, Bärbel, Oberwinkler, Heike, Herold, Nikolas, Briggs, John A. G., Müller, Barbara, Grünewald, Kay, Kräusslich, Hans-Georg
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Structure and Assembly
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097806/
https://ncbi.nlm.nih.gov/pubmed/24789788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00428-14
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