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Human Papillomavirus E7 Induces Rereplication in Response to DNA Damage

Human papillomavirus (HPV) infection is necessary but not sufficient for cervical carcinogenesis. Genomic instability caused by HPV allows cells to acquire additional mutations required for malignant transformation. Genomic instability in the form of polyploidy has been demonstrated to play an impor...

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Bibliografiske detaljer
Main Authors: Fan, Xueli, Liu, Yingwang, Heilman, Susan A., Chen, Jason J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554066/
https://ncbi.nlm.nih.gov/pubmed/23152514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02038-12
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