Phosphoinositide 3-kinase beta controls replication factor C assembly and function

Genomic integrity is preserved by the action of protein complexes that control DNA homeostasis. These include the sliding clamps, trimeric protein rings that are arranged around DNA by clamp loaders. Replication factor C (RFC) is the clamp loader for proliferating cell nuclear antigen, which acts on...

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Bibliographic Details
Main Authors: Redondo-Muñoz, Javier, Josefa Rodríguez, María, Silió, Virginia, Pérez-García, Vicente, María Valpuesta, José, Carrera, Ana C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553946/
https://ncbi.nlm.nih.gov/pubmed/23175608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1095
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