RECQL5 plays co-operative and complementary roles with WRN syndrome helicase

Humans have five RecQ helicases, whereas simpler organisms have only one. Little is known about whether and how these RecQ helicases co-operate and/or complement each other in response to cellular stress. Here we show that RECQL5 associates longer at laser-induced DNA double-strand breaks in the abs...

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Bibliografske podrobnosti
Main Authors: Popuri, Venkateswarlu, Huang, Jing, Ramamoorthy, Mahesh, Tadokoro, Takashi, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553943/
https://ncbi.nlm.nih.gov/pubmed/23180761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1134
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