In Vitro Analysis of Albendazole Sulfoxide Enantiomers Shows that (+)-(R)-Albendazole Sulfoxide Is the Active Enantiomer against Taenia solium

Albendazole is an anthelmintic drug widely used in the treatment of neurocysticercosis (NCC), an infection of the brain with Taenia solium cysts. However, drug levels of its active metabolite, albendazole sulfoxide (ABZSO), are erratic, likely resulting in decreased efficacy and suboptimal cure rate...

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Detaylı Bibliyografya
Asıl Yazarlar: Paredes, Adriana, de Campos Lourenço, Tiago, Marzal, Miguel, Rivera, Andrea, Dorny, Pierre, Mahanty, Siddhartha, Guerra-Giraldez, Cristina, García, Hector H., Nash, Theodore E., Cass, Quezia B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Susceptibility
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553705/
https://ncbi.nlm.nih.gov/pubmed/23229490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01465-12
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