In Vitro Analysis of Albendazole Sulfoxide Enantiomers Shows that (+)-(R)-Albendazole Sulfoxide Is the Active Enantiomer against Taenia solium

Albendazole is an anthelmintic drug widely used in the treatment of neurocysticercosis (NCC), an infection of the brain with Taenia solium cysts. However, drug levels of its active metabolite, albendazole sulfoxide (ABZSO), are erratic, likely resulting in decreased efficacy and suboptimal cure rate...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Paredes, Adriana, de Campos Lourenço, Tiago, Marzal, Miguel, Rivera, Andrea, Dorny, Pierre, Mahanty, Siddhartha, Guerra-Giraldez, Cristina, García, Hector H., Nash, Theodore E., Cass, Quezia B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553705/
https://ncbi.nlm.nih.gov/pubmed/23229490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01465-12
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge