In Vitro Analysis of Albendazole Sulfoxide Enantiomers Shows that (+)-(R)-Albendazole Sulfoxide Is the Active Enantiomer against Taenia solium

Albendazole is an anthelmintic drug widely used in the treatment of neurocysticercosis (NCC), an infection of the brain with Taenia solium cysts. However, drug levels of its active metabolite, albendazole sulfoxide (ABZSO), are erratic, likely resulting in decreased efficacy and suboptimal cure rate...

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Hlavní autoři: Paredes, Adriana, de Campos Lourenço, Tiago, Marzal, Miguel, Rivera, Andrea, Dorny, Pierre, Mahanty, Siddhartha, Guerra-Giraldez, Cristina, García, Hector H., Nash, Theodore E., Cass, Quezia B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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Susceptibility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553705/
https://ncbi.nlm.nih.gov/pubmed/23229490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01465-12
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