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Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients

BACKGROUND: Prostate cancer cell growth is dependent upon androgen receptor (AR) activation, which is regulated by specific kinases. The aim of the current study is to establish if AR phosphorylation by Cdk1 or ERK1/2 is of prognostic significance. METHODS: Scansite 2.0 was utilised to predict which...

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書誌詳細
主要な著者: Willder, J M, Heng, S J, McCall, P, Adams, C E, Tannahill, C, Fyffe, G, Seywright, M, Horgan, P G, Leung, H Y, Underwood, M A, Edwards, J
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553508/
https://ncbi.nlm.nih.gov/pubmed/23321516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.480
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