Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients

PURPOSE: Prostate cancer growth is dependent upon androgen receptor (AR) activation, regulated via phosphorylation. Protein kinase C (PKC) is one kinase that can mediate AR phosphorylation. This study aimed to establish if AR phosphorylation by PKC is of prognostic significance. METHODS: Immunohisto...

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Pubblicato in:Oncotarget
Autori principali: Patek, SC, Willder, JM, Heng, JS, Taylor, B, Horgan, PG, Leung, HY, Underwood, MA, Edwards, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354877/
https://ncbi.nlm.nih.gov/pubmed/27902483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13608
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