Upregulation of MAPK pathway is associated with survival in castrate-resistant prostate cancer

BACKGROUND: Recent evidence has implicated the MAP kinase (MAPK) pathway with the development of castrate-resistant prostate cancer (CRPC). We have previously reported gene amplification of critical members of this pathway with the development of castrate-resistant disease. In addition, we have show...

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Autors principals: Mukherjee, R, McGuinness, D H, McCall, P, Underwood, M A, Seywright, M, Orange, C, Edwards, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111196/
https://ncbi.nlm.nih.gov/pubmed/21559022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.163
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