NFκB signalling is upregulated in a subset of castrate-resistant prostate cancer patients and correlates with disease progression

BACKGROUND: Cell line models suggest that activation of NFκB is associated with progression of prostate cancer. This pathway may be a therapeutic target if these observations translate to clinical specimens. METHODS: Immunohistochemistry measured NFκBp65 (p65), NFκBp65 nuclear localisation signal (N...

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Autors principals: McCall, P, Bennett, L, Ahmad, I, MacKenzie, L M, Forbes, I W G, Leung, H Y, Sansom, O J, Orange, C, Seywright, M, Underwood, M A, Edwards, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493754/
https://ncbi.nlm.nih.gov/pubmed/23093296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.372
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